Efficacy of Sahajna (Moringa Oleifera) among Obese Women due to PCOS (Ikiyas-E-Khusyatur Reham): A Randomized Single Blind Study
Abstract
Background and Objective: PCOS is a heterogeneous, multisystem endocrinopathy in reproductive age women characterized by menstrual abnormalities, oligo /anovulation and hyper androgenism. These signs and symptoms vary widely within Individuals, overtime women with this endocrine disorder also have higher rates of dyslipidemia, obesity and insulin resistance, which increase long term health risks. Objective was to evaluate the efficacy of Sahajna (Moringa Oleifera) among obese women due to PCOS.
Methodology: This was a prospective– a randomized single blind study, to scientifically evaluate the efficacy of Sahajna in obese women. The present study was conducted in Govt.Nizamia General Hospital during the years of 2019 – 2021. 40 obese patients with the history of PCOD were registered from outpatient department of GNGH, out of which 30 patient were selected for clinical trial who has given consent for research study. A single group of 30 patients were selected for the study and patients were selected randomly. Study medicine is given to all the patients for a period of 3 months. Results were divided on the basis of subjective and objective parameters Overall results were assessed by Chi -square test.
Results: Analysis of data shows overall therapeutic response based on the subjective and objective parameter in this study were assessed as excellent, good, satisfactory and poor. The patients were satisfied by reduction of weight and improve their personality.
Conclusion: It is observed that the patients had good response with this medicine (sufoof–e-Sahajna) Marked reduction of weight observed by analyzing of BMI before and after completion of therapy for 3 months. It was noted that out of 30 patients 16.7% (n=5) patients were got excellent relief. 46.7% (n=14) patients showed good relief, 33.3% (n=10) patients showed satisfactory relief and 3.3% (n=1) patient showed poor response.
References
2.AllamaNajeebuddeinSamarqandi‘Sharhe Asbab’ 2009 published by Idarakitab-ul-shifa, page no112.
3.Allama Hakeem NajmulGani, Rampuri ‘KhazanulAdvia’ published byIdarakitab-ul-shifa, page no875-876.
4.AllamaKabeerudeen,’ Makhzan-ul-Mufradat’ Edition II published by Aijaz publishing house2012, page no- 272-273.
5.Avicenna, Mazhararishah, T.PK, ‘The cannon of medicine’ 2007 Edition. Published by syedAsad Hussain for Idrakitabulshifa, chapter -2, section 1, page no-300-320.
6.Abdul Al Hassan, Ali bin RbbonTabbri,’ FirdosulHikmath’, 6 Edition 2010 June, published by IdaraKitabulshifa, page no-112.
7.Ahmed K R SharahAsbab, Urdu translated by Sharif Khan, year 1980, page no-153.
8.Akbar Arzani, Tib e Akbar, page no-604. .
9.Carol Brannon, MS, RD, LD Understanding PCOS, year2008, page no-1-5.
10.Carlos Moranl, Monica Arriaga, Obesity in Polycystic ovary syndrome, 76.
11.D.C.Dutta, Text book of Gynaecology, 5th Edition, published by New Central book agency pvt Ltd, 8/1 chinthamani Das lane Calcutta700009, page no-440-443.
12.Duru Shah M.D, R.KBhatnaM.D, Safala Shroff M.D, The polycystic ovary, page no-1-100, year2004.
13Dr.K. M. Nadkarni, ‘Indian MetriaMedica’, 29th Edition, volume-1, published by popular prakasan, page no-810-816.
14.E.Sterling, Hormone levels and PCOS, year 2011.
15.Edmund R Novak, Text book of Gynaecology, 12th Edition, page no- 96-108, 161-180., 876-885, year-2006.
16..Farhan Ahmed, QudsiaNizami, M, Aslam, classification of unani drugs, 2005, page no- 321, 432, 433,434.
17. Griffin J.E and Ojeda, S.R Textbook of Endocrine physiology, 3rd Edition 1996
18.Glossary of Indian medicinal plants, page no-13
19.HakeemKaberuddin ‘Kitab Al Akseer’ published byAijaz publish press, New Delhi, 2003 volume-2, page no-1358-1359.
20..Hakeem Abdul Razzakh, TalimulQabila, vol-4, page no-206, 225.
21..Jillions, Kitab Fil Mizaj, 1st Edition, Aligarh, Ibn Sina Academy, year 2008. John Stud, Progress in obstetrics and gynaecology, vol-2, page no-365,363, year 2000.
22.JohnHaekins, Shaw’s text book of gynaecology,8 Edition, page no-23-38, 311,312.
23.Jaffcoate, Principles of gynaecology, 5th Edition, page no-31, 56, 63, 69,188, 508, year 1997.
24.JonarthanS.Berek ‘Berek&Norak’s Gynaecology 14th Edition published by Wolters Kluwa (India) pvt Ltd. New Delhi, pageno-1057-1058.
25.John Eden, the History of PCOS.
26.Kaberuddin in Tarzuma e Kabir, vol-3, page no- 310.
27. K.Sembulingam, P.Sembulingam: Essential of Medical physiology, 3rd Edition, page no-319-337
28.Leon Speroff, Clinical gynaecologic endocrinology and infertility, 5th Edition, page no- 34,41, 146, year1983.
29. Lawrence M Tierney, Current medical diagnosis and treatment,4th Edition, page no-749, year 2001.
30.L.Prakashamreddy, Fundamentals of medical physiology, 2nd Edition Page no-433-442, year2001 Edition.
31.MisbahulHikmaty, page no-371.
32.Marsh K Brand – Miller J (August 2005) ‘The optimal dietfor women with polycystic ovarian syndrome’ Dr. J. Nutur 94(2), 154-65.
33..Michel T.Sheehan, Polycystic Ovarian Syndrome, Diagnosis and Management year2004, volume2, page no-13-27.
34.NigramiS.TarikheTib 4th Edition, New Delhi, Quami Council BaraeFarogh Urdu Zaban, 20049.
35.Rotterdam, ESHRE/ASRM- Sponsored, PCOS, Consensus, Workshop, Group Revised2003 consensus on diagnostic criteria and long-term health risks related to poly cystic ovary syndrome. FertilSteril., year2004 Jan, 81(1), page no-19-25.
36. R.J.Slade, Key topics in obstetrics& gynaecology, 2nd Edition, page no-104.
37..T.M.Barber, Obesity and Polycystic ovary syndrome, Clinical Endocrinology, year 2006, page no137-145.
38.VG Pudubidri, SN Dafiflory, ‘Shaw’s Text book of Gynaecology ‘15th Edition published by Relax India private limited, New Delhi, page no-525-527.
39.Waseem Ahmed Azmi, Amraz e Nizwan, page no-382
40.Yoganarasimhan, Medicinal plants of India, volume-2, year 2005.
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