Journal of Research in Biomedical Sciences <p>Biomedical Research is a scientific open access journal that specifies and describes the development activities conducted in the field of biomedicine research. This journal encompasses the study related to microbiology, biochemistry, clinical, medical, computational and engineering aspects relevant to biomedical sciences. Articles will be also considered from related analysis from cell biology, developmental biology, translational medicine, biomedical research, biomedicine, biomedical science, biomedical informatics, biomedical diagnostics, biomedical ethics, biomedical therapy, medical research, clinical research, physiology, pharmacology, reverse pharmacology, Systems and networking pharmacology, TCAM, personalized medicine disciplines.&nbsp;Submission of important articles containing advanced research output aiding in forwarding the subject are most welcome. The wide scope of the journal will aid in contributing a great measure of scientific information related to the advances in towards better healthcare. <a href="">Submit Online</a></p> <p><br><br></p> Reverse Publications en-US Journal of Research in Biomedical Sciences <p><strong>Copyright and Licensing</strong></p> <p>For all articles published inJRBMS journal, copyright is retained by the authors. Articles are licensed under an open access Creative Commons CC BY 4.0 licenses, meaning that anyone may download and read the paper for free. In addition, the article may be reused and quoted provided that the original published version is cited. These conditions allow for maximum use and exposure of the work, while ensuring that the authors receive proper credit.</p> <p>In exceptional circumstances articles may be licensed differently. If you have specific condition (such as one linked to funding) that does not allow this license, please mention this to the editorial office of the journal at submission. Exceptions will be granted at the discretion of the publisher.</p> <p><strong>Reproducing Published Material from other Publishers</strong></p> <p>It is absolutely essential that authors obtain permission to reproduce any published material (figures, schemes, tables or any extract of a text) which does not fall into the public domain, or for which they do not hold the copyright. Permission should be requested by the authors from the copyright holder (usually the Publisher, please refer to the imprint of the individual publications to identify the copyright holder).</p> <p>Permission&nbsp;<strong>is required</strong>&nbsp;for:</p> <ol> <li>Your own works published by other Publishers and for which you did not retain copyright.</li> <li>Substantial extracts from anyones' works or a series of works.</li> <li>Use of Tables, Graphs, Charts, Schemes and Artworks if they are unaltered or slightly modified.</li> <li>Photographs for which you do not hold copyright.</li> </ol> <p>Permission&nbsp;<strong>is not required</strong>&nbsp;for:</p> <ol> <li>Reconstruction of your&nbsp;<em>own</em>&nbsp;table with data already published elsewhere. Please notice that in this case you must cite the source of the data in the form of either "Data from..." or "Adapted from...".</li> <li>Reasonably short quotes are considered&nbsp;<em>fair use</em>&nbsp;and therefore do not require permission.</li> <li>Graphs, Charts, Schemes and Artworks that are completely redrawn by the authors and significantly changed beyond recognition do not require permission.</li> </ol> <p><strong>Obtaining Permission</strong></p> <p>In order to avoid unnecessary delays in the publication process, you should start obtaining permissions as early as possible. If in any doubt about the copyright, apply for permission. IJRPHR cannot publish material from other publications without permission.</p> <p>The copyright holder may give you instructions on the form of acknowledgment to be followed; otherwise follow the style: "Reproduced with permission from [author], [book/journal title]; published by [publisher], [year].' at the end of the caption of the Table, Figure or Scheme.</p> Screening of minimal inhibitory & fungicidal concentration (MIC & MFC) Of Purified Thurusu ( Copper Sulphate) <p><em>Thurusu </em>or &nbsp;Crude copper sulphate(CuSo4) or is used as a raw drug in Siddha system of Medicine, it is available in nature and prepared synthetically by boiling Copper with Sulfuric acid. Chemically it exists in two forms hydrated form copper sulphate pentahydrate, it is blue in colour and anhydrous form copper sulphate ,it is pale green or grey white in colour. It is used after purification as a single drug or one of the ingredients in some metallo mineral formulations, it is widely used for external applications and internal formulations it has astringent, emetic, tonic, caustic and antiseptic actions, <em>thurusu</em> is normally used to heal ulcers, ulcers in male genital organ, eye diseases, <em>tiridhodam</em> etc .</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Hence in this pretext the fungicidal&nbsp; concentration of purified <em>thurusu</em> is validated by Minimal inhibitory concentration (MIC) and Minimal fungicidal concentration (MFC) methods.The MFC test allows determination of the minimum concentration of an agent necessary to achieve a &nbsp;fungicidal effect. It is worth noting, however, that the duration of time the antimicrobial is in contact with the test organism is quite long for this method, on the order of 18 hours. Thus, the test truly does determine the&nbsp;minimum&nbsp;concentration needed to kill the test organism, since all other parameters are conducive to biocidal effect. The MFC test can be a good and relatively inexpensive tool to rank a great number of antimicrobial agents by potency, for screening purposes. The MFC test can be used to evaluate formulation problems wherein the formulator suspects that the active ingredient is being “bound up” by other ingredients. The theory is that the MFC will be worse for a formula that has a portion of its active ingredient chemically combined with other ingredients, thus not available to kill microorganisms in the suspension.</p> Ethel Shiny S Bharath Christian Gomathi P Copyright (c) 2023 Journal of Research in Biomedical Sciences 2023-03-26 2023-03-26 5 1 136 140 10.124583/jrbms.v5i1.115