Comparative study on Characterization of dry fruit Terminalia chebula Linn. with seeds and without seeds

  • G. Sakthi PG Scholar, Dept. of Siddha Toxicology, Dr. M. G. R. Medical University, Chennai.
  • S. R. Pholtan Rajeev PG Scholar, Dept. of Siddha Toxicology, Dr. M. G. R. Medical University, Chennai.
Keywords: Terminalia chebula, Characterization of Raw Material, PLIM Guidelines

Abstract

This research aim concluded as; evaluated the standardization of purification of Terminalia chebula fruit as per siddha text references. Objectives were satisfied as; Standardized the purification process of dry fruit of Terminalia chebula in two methods. As per PLIM guideline and to develop the Standard Operating Procedure (SOP) for purification of dry fruit of Terminalia chebula with comparative study of sample 1(TC1) and sample 2 (TC2) Purified sample was very good medicinal valued than the un-purified sample (with seed powder sample). Finally concluded as, seed removal dry pulp of Terminalia chebula is very good medicinal remedy for single or poly herbal formulation in herbal medicines respectively.

References

BIBILIOGRAPHY
1. Sarasa D, Sridhar S, Prabakaran E. Effect of an antidiabetic extract of Trigonella foenum-graecum on normal and alloxan induced diabetic mice. Int J Pharmacy Pharmaceutical Sci 2012;4(1):63-65.
2. Agarwal M, Sharma P, Kushwaha S. Antifertility efficacy of 50% ethanolic extract of Calendula officinalis in male rats. Int J Pharmacy Pharmaceutical Sci 2011;3(5):192-196.
3. Gupta PC. Withania coagulans Dunal- An Overview. Int J Pharmaceutical Sci Review Research 2012;12(2):68-71.
4. World Health Organization. Summary of WHO guidelines for the assessment of herbal medicines. Herbal Gram 1993;28:13-14.
5. Naik GH, Priyadarsini KI, Naik DB, Gangabhagirathi R, Mohan H. Studies on the aqueous extract of Terminalia chebula as a potent antioxidant and a probable radioprotector. Phytomedicine 2004;11:530-38.
6. Ayyanara M, Ignacimuthu S. Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats in India. J Ethnopharmacol 2011;134:851-64.
7. Aneja KR, Joshi R. Evaluation of antimicrobial properties of fruit extracts of Terminalia chebula against dental caries pathogens. Jundishapur J Microbiol 2009;2(3):105-11.
8. Pulliah T. Encyclopedia of world medicinal plants. New Delhi, India: Regency Pub Vol 4, pp1931-1934.
9. Kumar KJ. Effect of geographical variation on contents of tannic acid, gallic acid, chebulinic acid and ethyl gallate in Terminalia chebula. Natural Products 2006;2(3-4):170-75.
10. Juang LJ, Sheu SJ, Lin TC. Determination of hydrolyzable tannins in the fruit of Terminalia chebula Retz. by high-performance liquid chromatography and capillary electrophoresis. J Sep Sci 2004;27(9):718–24.
11. Srivastava A, Chandra A, Singh M, Jamal F, Rastogi P, Rajendran SM, Bansode FW, Lakshmi V. Inhibition of hyaluronidase activity of human and rat spermatozoa in vitro and antispermatogenic activity in rats in vivo by Terminalia chebula, a flavonoid rich plant. Reproductive Toxicol 2010;29:214–24.
12. Kundu AP, Mahato SB. Triterpenoids and their glycosides from Terminalia chebula. Phytochemistry1993;32(4):999-1002.
13. Saleem A, Husheem M, Harkonen P, Pihlaja K. Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula Retz. Fruit. J Ethnopharmacol 2002;81:327-36.
14. Panunto W, Jaijoy K, Lerdvuthisopon N, Lertprasertsuke N, Jiruntanat N, Soonthornchareonnon N, Sireeratawong S. Acute and chronic toxicity studies of the water extract from dried fruits of Terminalia chebula Rezt. in rats. Int J Applied Research in Natural Products 2011;3(4):36-43.
15. Prasad L, Khan TH, Jahangir T, Sultana S. Chemomodulatory effects of Terminalia chebula against nickel chloride induced oxidative stress and tumor promotion response in male Wistar rats. J Trace Elements in Medicine and Biology 2006;20:233–39.
16. Kaur S, Michael H, Arora S, Harkonen PL, Kumar S. The in vitro cytotoxic and apoptotic activity of Triphala-an Indian herbal drug. J Ethnopharmacol 2005;97:15–20.
17. Usha C, Satyanarayanan R and Velmurugan A. Use of an aqueous extract of Terminalia chebula as an anticaries agent: A clinical study. Indian J Dent Res 2007;18(4):152-56.
18. Kirtikar KR, Basu BD. Terminalia chebula In: Indian Medicinal Plants, 2ndeds, Allahabad, India: Lolit Mohan Basu Pub 1935.p. 1020-23.
19. Kim JH, Koo YC, Hong CO, Yang SY, Jun W, Lee KW. Mutagenicity and oral toxicity studies of Terminalia chebula. Phytotherapy Res 2011 May 2 [Epub ahead of print].
20. Sato Y, Oketani H, Singyouchi K, Ohtsubo T, Kihara M, Shibata H and Higuti T. Extraction and purification of effective antimicrobial constituents of Terminalia chebula Retz. against methicillin-resistant Staphylococcus aureus. Bio Pharm Bull 1997;20(4): 401-04.
21. Ahmad I, Mehmood Z, Mohammad F. Screening of some Indian medicinal plants for their antimicrobial properties. J Ethnopharmacol 1998;62:183-93.
22. Malekzadeh F, Ehsanifar H, Shahamat M, Levin M, Colwell RR. Antibacterial activity of black myrobalan (Terminalia chebula Retz) against Helicobacter pylori. J Antimicrobial Agents 2001;18:85–88.
23. Kim HG, Cho JH, Jeong EY, Lim JH, Lee SH, Lee HS. Growth-inhibiting activity of active component isolated from Terminalia chebula fruits against intestinal bacteria. J Food Prot 2006;69(9):2205-9.
Published
2020-07-01
How to Cite
1.
G. Sakthi, S. R. Pholtan Rajeev. Comparative study on Characterization of dry fruit Terminalia chebula Linn. with seeds and without seeds. J Res Bio Med Sci [Internet]. 2020Jul.1 [cited 2025Oct.30];3(2):62-1. Available from: http://biosci.in/index.php/jrbms/article/view/70
Section
Articles